Signature Personalized Patient Care

Signature Personalized Patient Care

Patient Risk Information

How does it work?

Signature™ Cutting GuidesInstead of relying on two-dimensional x-rays to plan your surgery, the Signature™ system uses an MRI of your knee in conjunction with computer software to create a 3-D image of your unique knee joint. The MRI is also used to create custom femoral (thighbone) and tibial (shinbone) positioning guides that fit directly onto your unique anatomy. With the combination of the MRI and Signature™ positioning guides, your surgeon has access to a greater level of detail and precision for implant positioning and alignment before the procedure. The result? Patient-specific positioning of your knee implant.


  • Precise, personalized approach to knee replacement
  • Based on your specific anatomy
  • Uses 3-D MRI technology instead of 2-D x-rays
  • Patient-matched guides help surgeons with implant positioning



With the Signature™ system for the Oxford® Partial Knee, your preoperative experience will be similar to most total knee patients, with one exception. An MRI of your affected leg will be required. A typical MRI scan lasts about 20 minutes. The scan will be performed only on your hip, knee and ankle, so your head will remain outside the machine. The MRI is used for preoperative planning by your surgeon and for the design and manufacture of the Signature™ personalized positioning guides that will be used during your partial knee replacement.


During surgery, there are significant differences between traditional and Signature™ knee replacement techniques.

Traditional Knee Replacement - During traditional knee replacement, metal instruments are used to remove the damaged bone and cartilage, confirm implant sizing, and establish proper implant positioning and alignment on the bone. Additionally, instruments are sometimes placed inside the femur (thighbone) and/or tibia (shinbone) to assist with implant alignment and positioning.

  • Metal instruments establish implant position and alignment
  • Metal rods are sometimes placed inside the bone canal

Signature™ Knee Replacement - With the Signature™ system, custom guides are placed directly onto your unique anatomy to assist the surgeon with implant alignment and positioning. These personalized guides are created from the 3-D MRI of your knee.

  • Custom guides are placed directly onto your knee anatomy
  • Custom guides have implant position and alignment built into their design

**A collaborative partnership with Materialise, N.V.

All trademarks herein are the property of Biomet, Inc. or its subsidiaries unless otherwise indicated.

Biomet is a manufacturer of orthopedic implants and does not practice medicine. Only an orthopedic surgeon can determine what treatment is appropriate. Individual results of total joint replacement may vary. The life of any implant will depend on your weight, age, activity level, and other factors. For more information on risks, warnings, and possible adverse effects, see the Patient Risk Information section found within Always ask your doctor if you have any questions regarding your particular condition or treatment options.